Post transplant thrombotic microangiopathy
نویسندگان
چکیده
منابع مشابه
Transplant-Associated Thrombotic Microangiopathy in Childhood
Vascular endothelium is damaged by toxic agents during the preparation regimen for stem cell transplantation. Microthrombi develop in small arterioles and capillaries and cause partial obstruction. Erithrocytes are subjected to mechanical trauma, and as a result, to hemolysis and fragmentation. Patients have clinical symptoms similar to thrombotic thrombocytopenic purpura (TTP) and Hemolytic Ur...
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Transplant-associated thrombotic microangiopathy (TA-TMA) occurs frequently after hematopoietic stem cell transplantation (HSCT) and can lead to significant morbidity and mortality. There are no data addressing individual susceptibility to TA-TMA. We performed a hypothesis-driven analysis of 17 candidate genes known to play a role in complement activation as part of a prospective study of TMA i...
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Thrombotic microangiopathy (TMA) is characterized by aggregation of platelets in the renal and/or systemic circulation, thrombocytopenia and intravascular haemolysis. TMA is well recognized in the setting of renal transplantation and has been attributed to a variety of aetiologies such as recurrence of original disease, use of calcineurin inhibitors, acute rejection and viral infections [1,2]. ...
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Thrombotic microangiopathy (TMA) is a known complication of HIV infection. Endothelial cell injury appears to be the primary event causing platelet activation and deposition in the microvasculature. Direct cytopathic roles of HIV as well as other factors such as malignancy, drugs, and infectious agents have been implicated in the pathogenesis of HIV-TMA. Although the the majority of patients pr...
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Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare clinical entity where tumor cell embolisms in pulmonary circulation induce thrombotic microangiopathy (TMA), respiratory failure, and subacute cor pulmonale. We describe 3 cases of PTTM that presented as the initial manifestation of metastatic gastric adenocarcinoma with TMA and pulmonary infiltrates. All 3 cases had similar clinical a...
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ژورنال
عنوان ژورنال: Indian Journal of Transplantation
سال: 2014
ISSN: 2212-0017
DOI: 10.1016/j.ijt.2014.11.002